02/04/2024
LINCam : Working principleWe present a detector system with a microchannel plate based photomultiplier tube (MCP-PMT) and its application for fluorescence lifetime imaging (FLIM) in visible light. A capacity coupled imaging technique (charge image) combined with a charge division anode is employed for the positional readout. Using an artificial neural network's (ANN) computation model we are able to reconstruct the p...
02/04/2024
SPAD LINCam comparisonA recent addition to the toolboxof super-resolution microscopy methodsis fluorescence-lifetime single-molecule local-ization microscopy(FL-SMLM).Thesynergyof SMLMandfluorescence-lifetime imaging microscopy(FLIM) combines superior imagere solution with lifetime information and can be realized using two complementary experimental approaches: confocal-laser scan-ning microscopy(CLSM) or &...
29/03/2019
Experimental Evaluation of Resistive Glass Ion OpticsResistive Glass is formed into a Reflectron Lens and evaluated for resistance uniformity and directly compared to the performance of a stacked ring assembly Reflectron. Results show that Resistive Glass is well suited for making ion optics components that simplify cleaning and replacement.
29/03/2019
HI-QE PaperBased on conventional S-20 processes, a new series of high quantum efficiency (QE) photocathodes has been developed that can be specifically tuned for use in the ultraviolet, blue or green regions of the spectrum. The QE values exceed 30% at maximum response, and the dark count rate is found to be as low as 30 Hz/cm2 at room temperature. This combination of properties along with a fast tempo...
29/03/2019
High Dynamic Range Ion Detection Using Channel Electron MultipliersImproving the dynamic range of a channel electron multiplier to operate at high output current. The paper discusses the addition of discrete dynodes to a six-channel electron multiplier to achieve this operation and examines the effect on the lifetime of the detector.
29/03/2019
HQE S20 Photocathodes in Photon Counting ApplicationsHigh Quantum Efficiency S20 Photocathodes in Photon Counting Applications
Improvements were done to a standard S20 photocathode that increase the quantum efficiency by up to 50%. Test results on a Chevron style MCP-PMT are presented.
29/03/2019
Improved Lifetime and Performance for Your Mass SpectrometerThis article discusses how improvements to electron multipliers bring extended lifetime and higher gain for better mass spectrometer analysis.
29/03/2019
Improving MALDI-TOF Performance with Practical Implementation of Very High Post-AccelerationThis paper discusses ways to improve MALDI-TOF performance in ion masses in excess of 100kDa by applying very high post-acceleration voltages.
29/03/2019
Improving Quantification in Time of Flight (TOF) Mass Spectrometers by Optimizing Detector ResponseThis paper looks at ways to optimize the operating parameters of a Time of Flight detector. The paper examines the effects of various MCPs, voltages and gain on the detector.
31/03/2019
Miniature Ion Detectors for Mass Spectrometers Help Move Laboratory Analysis into the FieldThis article describes advancements in the development of miniature ion detectors to facilitate the implementation of truly portable mass spectrometers, residual gas analyzers and other analytical instruments. A wide variety of detectors are available.
31/03/2019
Performance Characteristics of Detectors Operated in Harsh EnvironmentsThis paper discusses the effect of detector degredation when exposed to high atmospheric pressure operation. A comparison of channel electron multipliers in single- and six-channel types were evaluated as was a new MountingPad rimless Microchannel Plate.
31/03/2019
Performance Characterization Of A Simultaneous Positive and Negative Ion Detector For Mass Spectrometry ApplicationsRecent advances in shadow mask and laser ablation technology have opened up new possibilities for making compact segmented detectors.The active area of the microchannel plate can now be effectively partitioned into multiple areas offering specific performance capabilities. Separate areas could be effectively biased to preferentially detect either positively or negatively charged particles.
31/03/2019
Quantum Sub Miniature MCP DetectorThe Development of a Micro-Miniature Microchannel Plate Based Detector For Mass Spectrometry Applications
31/03/2019
Raising the Bar on Electron Multiplier Operation at Elevated PressuresThis paper explores the boundaries of electron multiplication for amplification at pressures above 1x10-4 Torr. Using gain, voltage and dark current measurements in differing multiplier geometries, the maximum operating pressure as a function of voltage and detector gain is presented.
31/03/2019
Reducing Detector Time Jitter to improve Mass Resolution in a Time of Flight Mass SpectrometerThe effects of combining previous research regarding optimizing Microchannel Plates with regards to both optimal resolution parameters and MCP flatness to increase mass resolution by as much as 15%.